What really makes this vitamin so important is the fact that you probably never heard of it. PPQ (pyrroloquinoline quinone) tells us that there are countless components in whole food that haven’t been discovered yet. PQQ is a nutrient that was discovered in the later part of 1970’s and is just beginning to be understood. Pyrroloquinoline quinone is an organic element which is obtained from the bacteria and is a reduction-oxidization cofactor like nicotinamides and flavins. Pyrroloquinoline quinone (PQQ) is considered to be one of the important nutrients for humans and is thought to be a vitamin. It is a member of group B complex vitamins. It was found by J.G. Hauge which called it the third redox cofactor. It is found to be water soluble. It causes activation of various signaling molecules. It contains vitamin B12 along with quinone in its structure. PQQ was first discovered in 1979 as an essential cofactor for alchohol dehydrogenase, the enzyme that is responsible for helping the liver metabolize alcohol.
In bacteria, PQQ stimulates growth and serves as a cofactor for a special class of dehydrogenases/oxidoreductases. As such, PQQ is a key regulator of cellular function and is involved in signal transduction processes involved in cellular growth, development, differentiation and survival. It is also as an extremely powerful antioxidant capable of catalyzing continuous redox cycling (the ability to catalyze repeated oxidation and reduction reactions) to a much greater degree compared to other antioxidants.
Functions and benefits of Pyrroloquinoline Quinone
- Most notably, PQQ stimulates the spontaneous growth of new mitochondria in aging cells, and activates genes that govern mitochondrial reproduction, protection, and repair.
- Pyrroloquinoline quinone is important for the mitochondria where it supports its health. It promotes biogenesis in mitochondria. Therefore it improves the utilization of energy in them.
- It acts as an ant oxidant and causes removal of dangerous substance form the body. In this way it provides protection from the oxidative stress.
- It is found to causes breakdown of amino acids.
- n 2010, researchers at the University of California at Davis released a peer-reviewed publication showing that PQQ’s critical role in growth and development stems from its unique ability to activate cell signaling pathways directly involved in cellular energy metabolism, development, and function.
- Because of its important antioxidant functions as well as signaling activation it can use to protect an individual from aging. It acts as an anti-aging vitamin in our body.
- New research is forthcoming related to cognitive function as it relates to such conditions as memory loss, Parkinson disease and Alzheimer’s disease.
- Research shows that that PQQ supports heart cell function and promotes good blood flow in the heart muscle.
- PQQ also interacts with the -ras genes that accelerate the growth of cancer. It seems to turn them off and prevent the spread of cancers throughout cancer-prone tissues. PQQ fights diabetes and cancers and helps you lose weight. Aren’t you glad you know about PQQ?
Deficiency of Pyrroloquinoline Quinone
- Lack of this important vitamin results in slowing of mitochondrial energy utilization process. The biogenesis of mitochondria cannot take place effectively.
- Its antioxidant beneficial property can be depressed and our brain and heart would be at increases risk of getting harm from the oxidative stress.
- Deficiency of PQQ can also lead to poor cognitive functions.
Food sources of Pyrroloquinoline Quinone
- Apple, banana, cabbage, carrots, celery, edamamespinach, orange, parsley, green peppers, green tea, kiwi fruit, papaya, potatoes, tomato and tofu.
- Since PQQ may be vital to our durability and longevity we should eat a wide variety of whole foods
- Vitamin B12 (Cobalamin) : Daily Requirement, Function, Benefits And Food Source That Everyone Should Know. (blissreturned.wordpress.com)